Top 10 Investors in B2B (2025)

• Last Updated: July 07, 2025

Total Investments

5,239

Successful Exits

567

Active Investors

172

Top B2B Investment Guide

Introduction to B2B Investment Landscape

The B2B sector has attracted significant investment attention. In this comprehensive guide, we'll explore the most active and successful investors in B2B, based on their investment history, portfolio performance, and industry expertise.

How We Ranked B2B Investors

Our rankings are based on several key factors:

  • Number of investments in B2B
  • Successful exits in the sector
  • Portfolio company performance
  • Industry expertise and network
  • Overall investment track record
Profile photo of Norwest Venture Partners

Norwest Venture Partners

Palo Alto, California, United States

Norwest is a global venture capital and growth equity investment firm that manages more than $7.5B in capital.
Finance Financial Services Consumer Venture Capital Health Care B2B Venture Capital
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Profile photo of Alchemist Accelerator

Alchemist Accelerator

San Francisco, California, United States

The Alchemist Accelerator is a venture-backed initiative focused on accelerating startups whose revenue comes from enterprises.
Health Care Software SaaS Biotechnology Medical Apps Manufacturing B2B Enterprise Software Accelerator
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Profile photo of Innova Memphis

Innova Memphis

Memphis, Tennessee, United States

Innova Memphis invests in early stage businesses related to biosciences, healthcare, technology, and AgTech.
Venture Capital Medical Logistics Supply Chain Management AgTech B2B Micro VC Venture Capital Government Office
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Profile photo of Acceleprise

Acceleprise

San Francisco, California, United States

Acceleprise invests in early stage B2B SaaS and enterprise technology companies and unifies the global technology community through mentors.
SaaS B2B Enterprise Software Accelerator
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Profile photo of Startup Wise Guys

Startup Wise Guys

Tallinn, Harjumaa, Estonia

Startup Wise Guys is the leading B2B startup accelerator in Europe.
Software FinTech SaaS B2B Cyber Security Enterprise Software Micro VC Accelerator
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Profile photo of Boomtown Accelerators

Boomtown Accelerators

Boulder, Colorado, United States

Boomtown's bespoke accelerator programs help startups turn ideas into profitable, scalable businesses.
Health Care Internet SaaS Internet of Things Mobile Advertising B2B Network Hardware Accelerator
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Elaia

Paris, Ile-de-France, France

Elaia is the digital & deep tech VC firm.
Financial Services Venture Capital Software Artificial Intelligence B2B Venture Capital
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FREES FUND

Beijing, Beijing, China

FREES FUND is a venture capital firm that provides both early and growth stage investment to technology startups in both China and the U.S.
Energy E-Commerce Education FinTech Medical Virtual Reality B2B Consumer Goods Venture Capital
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Profile photo of AlphaLab

AlphaLab

Pittsburgh, Pennsylvania, United States

AlphaLab is a nationally ranked software accelerator helping early-stage tech companies quickly figure out the best way to build and grow.
Finance Energy E-Commerce FinTech Biotechnology Marketing Life Science Augmented Reality Virtual Reality Mobile Advertising B2B B2C Enterprise Retail Technology Accelerator
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Profile photo of Nauta Capital

Nauta Capital

London, England, United Kingdom

Nauta Capital is a pan-European Venture Capital firm investing in early stage technology companies.
Finance Venture Capital Software SaaS Cryptocurrency Blockchain B2B Venture Capital
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B2B Market Analysis and Trends

Key Findings

  • Average investments per investor: 30.5
  • Most common investor types: Venture Capital, Accelerator, Micro VC, Private Equity Firm, Angel Group
  • Success rate (exits/investments): 10.8%

Key Takeaways: B2B Investment Landscape

The B2B investment landscape continues to evolve and grow. These top investors have demonstrated consistent success in identifying and supporting promising startups in the sector. Whether you're a founder looking for investment or an aspiring investor in B2B, these individuals represent some of the most knowledgeable and active participants in the ecosystem.

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